Molecular BiologyMolecular CellPeer-reviewed
Alternative splicing decouples local from global PRC2 activity
Niccolò Arecco, Ivano Mocavini, Enrique Blanco…·Luciano Di Croce
The paper identifies an alternative splicing event in SUZ12 that generates two PRC2 subtypes, SUZ12-S and SUZ12-L, with distinct roles in PRC2 function and H3K27 methylation.
17 citations