Egg MVBs elicit an antimicrobial pathway to degrade paternal mitochondria after fertilization
Sharon Ben‐Hur, Sara Afar, Yoav Politi, Liron Gal, Ofra Golani, Ehud Sivan, Rebecca Haffner‐Krausz, Elina Maizenberg, Sima Peretz, Zvi Roth, Dorit Kalo, Nili Dezorella, David Morgenstern, Shmuel Pietrokovski, Keren Yacobi-Sharon, Eli Arama
The paper shows that egg-derived MVBs use the LAP pathway to eliminate paternal mitochondria in Drosophila, with potential parallels in mammals.
Nature Communications · Jul 8, 2024Peer-reviewedDevelopmental Biology