Bacterial membrane vesicles of Pseudomonas aeruginosa activate AMPK signaling through inhibition of mitochondrial complex III
Julia Müller, Marcel Kretschmer, Elise Opitsch, Svea Holland, José Manuel Borrero‐de Acuña, Dieter Jahn, Meina Neumann‐Schaal, André Wegner
This study shows that Pseudomonas aeruginosa membrane vesicles inhibit mitochondrial complex III, activate AMPK signaling, and reduce global protein synthesis in human lung cells.
PNAS Nexus · Jul 31, 2025Peer-reviewedCell Biology