Deep mutational scanning of an S. pneumoniae FMN riboswitch reveals robustness during mouse infection but diverging adaptive landscapes in response to targeting antibiotics
Rebecca Korn, Jon S. Anthony, Quinlan Furumo, Elizabeth C. Gray, Indu Warrier, Michelle M. Meyer
The paper uses deep mutational scanning to assess the fitness effects of FMN riboswitch mutations in S. pneumoniae under various conditions, revealing robustness during infection and diverging adaptive responses to antibiotics.
bioRxiv · Apr 17, 2025 · PreprintGenetics