Quinlan Furumo

Analysis of 3'-seq data from multiple E. coli studies identifies diverging results sets and raw data characteristics despite similar collection conditions

The paper analyzes 3'-seq data from multiple E. coli studies and identifies large disparities in raw data characteristics and strand-specific inconsistencies despite similar experimental conditions.

Deep mutational scanning of an S. pneumoniae FMN riboswitch reveals robustness during mouse infection but diverging adaptive landscapes in response to targeting antibiotics

The paper uses deep mutational scanning to assess the fitness effects of FMN riboswitch mutations in S. pneumoniae under various conditions, revealing robustness during infection and diverging adaptive responses to antibiotics.

PIPETS: A statistically informed, gene-annotation agnostic analysis method to study bacterial termination using 3'-end sequencing.

PIPETS is an R package for analyzing 3'-end sequencing data in bacteria, identifying termination signals more broadly than existing methods.