Michelle M. Meyer

Translation Inhibiting Antibiotics Induce an asRNA Regulating Purine Metabolism in S. pneumoniae TIGR4 via an ISL3 Insertion Derived Hybrid Promoter

Electrical Readout Strategies of GFET Biosensors for Real-World Requirements

This study compares amperometric and potentiometric readout strategies for GFET biosensors, finding that transconductance offers better detection limits but lower reproducibility, while Dirac point tracking provides higher robustness but worse limits of detection.

Assessing the conservation and targets of putative sRNAs in Streptococcus pneumoniae

This study identifies and characterizes 58 putative sRNAs in Streptococcus pneumoniae, assessing their conservation and predicting targets, with a focus on those potentially involved in virulence and carbon metabolism.

Analysis of 3'-seq data from multiple E. coli studies identifies diverging results sets and raw data characteristics despite similar collection conditions

The paper analyzes 3'-seq data from multiple E. coli studies and identifies large disparities in raw data characteristics and strand-specific inconsistencies despite similar experimental conditions.

Deep mutational scanning of an S. pneumoniae FMN riboswitch reveals robustness during mouse infection but diverging adaptive landscapes in response to targeting antibiotics

The paper uses deep mutational scanning to assess the fitness effects of FMN riboswitch mutations in S. pneumoniae under various conditions, revealing robustness during infection and diverging adaptive responses to antibiotics.

PIPETS: A statistically informed, gene-annotation agnostic analysis method to study bacterial termination using 3'-end sequencing.

PIPETS is an R package for analyzing 3'-end sequencing data in bacteria, identifying termination signals more broadly than existing methods.

Regulatory context drives conservation of glycine riboswitch aptamers

The paper uses graph clustering to analyze glycine riboswitch aptamers, showing that conservation depends on the regulated gene and that singleton aptamers likely originate from tandem riboswitches.