Dynamic translocation of Inside-Out proteins to the cell surface underlies cellular adaptation to cancer-induced stress
Tomasz Ślężak, Kelly M. O’Leary, Tanya Guevara Avella, Natalia Musiał, Jinyang Li, Anna Andrzejczak, Elizabeth F. Scott, Duc Anh Le, Anthony A. Kossiakoff
The paper identifies and characterizes Inside-Out (I-O) proteins on cancer cell surfaces, showing their dynamic trafficking and link to stress response mechanisms.
Proceedings of the National Academy of Sciences · Mar 24, 2026Peer-reviewedBiochemistry