Circulating cell-free DNA methylation profiles as noninvasive multiple sclerosis biomarkers: A proof-of-concept study
Hailu Fu, Kevin Y. Huang, Wen Zhu, Lili Zhang, Ravi Bandaru, Shruthi Venkatesh, Elizabeth Walker, Li Wang, Yaping Liu, Zongqi Xia
This study identifies circulating cell-free DNA methylation profiles as potential non-invasive biomarkers for multiple sclerosis, showing their ability to classify subtypes, estimate severity, and predict progression.
medRxiv · Feb 14, 2025 · PreprintGenetic & Genomic Medicine