Astrocyte modulation of synaptic plasticity mediated by activity-dependent Sonic hedgehog signaling
Anh Duc Le, Marissa Fu, Ashley Carper, Elizabeth Zegarowicz, Riya Kumar, Gloria Zacharias, A. Denise R. Garcia
This study shows that neural activity activates Sonic hedgehog signaling in astrocytes, leading to synapse-modifying molecule expression and experience-dependent structural plasticity.
Journal of Neuroscience · Feb 3, 2025Peer-reviewedNeuroscience