Structural details of amyloid beta oligomers in complex with human prion protein as revealed by solid-state MAS NMR spectroscopy
Anna S. König, Nadine S. Rösener, Lothar Gremer, Markus Tusche, Daniel Flender, Elke Reinartz, Wolfgang Hoyer, Philipp Neudecker, Dieter Willbold, Henrike Heise
This study uses solid-state MAS NMR to investigate the structure of Aβ oligomers bound to huPrP, revealing conformational heterogeneity and β-strand content.
Journal of Biological Chemistry · Jan 1, 2021Peer-reviewedMolecular Biology