Importin-β specific nuclear transport defects recapitulate phenotypic and transcriptional alterations seen in neurodegeneration
Jonathan Plessis‐Belair, Kathryn Ravano, Ellen Han, Aubrey Janniello, Catalina Molina, Roger B. Sher
The paper shows that Importin-β nuclear transport defects cause TDP-43 mislocalization and transcriptional changes linked to neurodegeneration.
bioRxiv · Feb 14, 2024 · PreprintNeuroscience