Effective imaging and treatment of Acute Myeloid Leukemia with radiotheranostics targeting the activated conformation of integrin-Beta2
Anju Wadhwa, Haley E. Johnson, Kondapa Naidu Bobba, Anil P. Bidkar, Ellis Mayne, Sham Rampersaud, Kamal Mandal, Abhilash Barpanda, Sanjana Prudhvi, Amrik S. Kang, Nancy Greenland, Dana J. Balitzer, Robin Peter, Athira Raveendran, Shubhankar Naik, , Robert R. Flavell
This study demonstrates promising preclinical efficacy of aITGB2-targeted radiotheranostics for selective imaging and therapy in AML.
bioRxiv · Aug 21, 2025 · PreprintCancer Biology