Parallelization of single-molecule binding kinetic measurements via protein barcode sequencing
Sebastian Hutchinson, Ghada H. Mansour, Ahmed Rehan, Adeline Pichard-Kostuch, Ellyn Redheuil, Brian D. Reed, Andrew D. Griffiths, Marco Ribezzi‐Crivellari
This paper introduces a method to parallelize single-molecule binding kinetic measurements using protein barcode sequencing, enabling rapid and multiplexed screening of protein libraries.
bioRxiv · Jun 5, 2025 · PreprintBiochemistry