Synergistic activation of RARb and RARg nuclear receptors restores cell specialization during stem cell differentiation by hijacking RARa-controlled programs
Aysis Koshy, Elodie Mathieux, François Stüder, Aude Bramoulle, Michèle Lieb, Bruno Maria Colombo, Hinrich Gronemeyer, Marco Antonio Mendoza-Parra
This study shows that activating RARβ and RARγ receptors with specific ligands enhances cell specialization during stem cell differentiation into neuronal and glial cell types.
Life Science Alliance · Nov 29, 2022Peer-reviewedMolecular Biology