Topaz1, an essential gene for murine spermatogenesis, down-regulates the expression of numerous testis-specific long non-coding RNAs.
Manon Chadourne, Elodie Poumerol, Luc Jouneau, Bruno Passet, Johan Castille, Eli Sellem, Éric Pailhoux, Béatrice Mandon‐Pepin
This paper investigates the role of Topaz1 in murine spermatogenesis, showing it stabilizes testis-specific long non-coding RNAs and is critical for terminal differentiation but not essential for fertility.
Frontiers in Cell and Developmental Biology · Jul 1, 2021Peer-reviewedDevelopmental Biology