Identification of the Col4a3-/- mouse as a model of chronic kidney disease-associated cachexia
Marie Buléon, Manon Brunet, Emma Ballongue, Victoire Ankaoua, Elsa Gutowski, Laure Monteillet, Rayane Benyahia, Guylène Feuillet, Stéphane Poitevin, Stéphane Burtey, Laetitia Koppe, Dominique Langin, Maria Rohm, Joost Peter Schanstra, Julie Klein, Pauline Morigny
The paper identifies the Col4a3-/- mouse as a model of CKD-associated cachexia, showing significant weight loss, muscle atrophy, and systemic inflammation.
bioRxiv · Oct 12, 2026 · PreprintPathology