The glucocorticoid dexamethasone influences motility of the sulfate-reducing bacterium Desulfovibrio desulfuricans by targeting the filament cap protein FliD
Elena Fajardo-Ruiz, Emanuel Kring, Dominik Schum, Sophie Brameyer, Robin Kretschmer, Tao Wang, J. Hesse, Isabella Gantner, Emma Weissert, Lisa Göbner, Lucas Milles, Tobias A. M. Gulder, Stephan A. Sieber, Kirsten Jung
This paper shows dexamethasone affects Desulfovibrio desulfuricans motility by binding to FliD, a flagellar cap protein, without relying on metabolism.
bioRxiv · Jul 7, 2026 · PreprintMicrobiology