Transcriptional memory is conferred by combined heritable maintenance and local removal of selective chromatin modifications
Paweł Mikulski, Sahar Tehrani, Anna Kogan, Izma Abdul‐Zani, Emer Shell, Louise James, Brent James Ryan, Lars E.T. Jansen
The paper identifies chromatin modifications and regulatory elements that enable long-term transcriptional memory of IFNγ exposure in immune cells.
Nature Structural & Molecular Biology · Apr 4, 2025Peer-reviewedMolecular Biology