Molecular BiologybioRxivPreprint
Cardiomyocyte-specific loss of Smyd5 leads to a robust activation of inflammatory signaling and heart failure in mice.
Ryan D. Bia, Samuel M. Hickenlooper, Mickey R. Miller…·Sarah Franklin
This study shows that loss of Smyd5 in cardiomyocytes causes inflammation and heart failure in mice by reducing H4K20me3 and increasing Il-6 expression.
DOI 10.64898/2026.09.02.748923