Anna A. Bakhtina

This study shows that loss of Smyd5 in cardiomyocytes causes inflammation and heart failure in mice by reducing H4K20me3 and increasing Il-6 expression.

This study isolates podocyte mitochondria from mice to show they have higher respiratory capacity than tubule mitochondria, with age- and sex-dependent differences.

The paper uses quantitative cross-linking and mass spectrometry data to cluster cross-links by their conformational state preferences, providing insights into protein conformational plasticity across different biological contexts.

This study combines quantitative proteomics and interactomics to analyze molecular differences between three human cell lines, revealing cell-type-specific changes in protein interactions and conformations.

The paper compares mitochondrial interactomes of podocytes and tubules in mouse kidney using quantitative cross-linking mass spectrometry, revealing distinct pathways and enzyme activities.

The paper uses cross-linking to study mitochondrial interactome changes in aging mouse muscle, finding age-related shifts in protein interactions linked to functional decline.

The paper uses XL-MS and iqPIR to compare mitochondrial protein interactions in healthy and failing murine hearts, identifying structural changes in metabolic machinery.

The paper identifies phosphosites that affect protein thermal stability by measuring stability differences between proteins and their phosphorylated forms at a proteomic scale.