Antibody targeting the anti-parallel topology of human telomeric G-quadruplex DNA
Nasab Reda, Sofia Muret, Clément Estève, Emilie Derathe, Maria Fidelia Susanto, Eve Pitot, Hugues Bonnet, Thomas Lavergne, Dennis Gómez, Jérôme Dejeu, Natale Scaramozzino, Éric Defrancq
This study develops an antibody that selectively recognizes the antiparallel topology of human telomeric G-quadruplex DNA, distinguishing it from parallel conformations.
bioRxiv · May 13, 2025 · PreprintBiochemistry