Oligodendrocyte progenitor cell responses to inflammatory demyelination with aging in mouse model of multiple sclerosis
Emily E. Fresenko, Camilla N. Bahri, Benjamin J. Burson, Noor F. Ahmed, Davin Packer, Benjamin J. Tabor, Bogdan Beirowski, Wenjing Sun, Michelle Ariana Wedemeyer, Cole A. Harrington
This study examines how aging affects oligodendrocyte progenitor cell (OPC) responses to inflammatory demyelination in a mouse model of multiple sclerosis, finding that both young and aged OPCs can differentiate into mature oligodendrocytes.
bioRxiv · Sep 22, 2025 · PreprintNeuroscience