Mechanical cues from muscle contraction regulate TGFβ signaling and epitenon formation during embryonic tendon development.
Emily R. King, Leonardo Campos, Joanna Smeeton, Nadeen O. Chahine, Alice H. Huang
The paper shows that muscle contraction regulates TGFβ signaling and epitenon formation during embryonic tendon development, leading to structural and functional deficits in paralyzed tendons.
bioRxiv · May 18, 2026 · PreprintDevelopmental Biology