Highly multiplexed mRNA quantitation with CRISPR-Cas13
Brian Kang, Jiayu Zhang, Michael P. Schwoerer, Amy N. Nelson, Emily Schoeman, Andrew Guo, Alexander Ploß, Cameron Myhrvold
This paper introduces qCARMEN, a CRISPR-Cas13-based RNA quantitation method that enables high-throughput, cost-effective analysis of over 4,500 gene-sample pairs, with applications in gene regulation and infection studies.
bioRxiv · Aug 16, 2023 · PreprintMolecular Biology