BioinformaticsBioinformaticsPeer-reviewed
One-Hot News: Drug Synergy Models Shortcut Molecular Features
Emine Beyza Candir, Halil İbrahim Kuru, Magnus Rattray…·Öznur Taştan
This paper shows that using one-hot encodings for drugs and cell lines in synergy prediction models can perform as well as or better than using molecular features, suggesting models rely more on identifiers than features.