Oral vancomycin treatment alters levels of indole derivatives and secondary bile acids modulating the expression of mTOR pathway genes in astrocytes during EAE
Paola Bianchimano, Paola Leone, Emma M. Smith, Cristina Gutiérrez‐Vázquez, Erli Wind-andersen, Gerold Bongers, Sebastian Cristancho, Howard L. Weiner, José C. Clemente, Stephanie K. Tankou
This study shows vancomycin improves EAE recovery by altering gut microbiota, indole derivatives, and secondary bile acids, which modulate mTOR pathway gene expression in astrocytes.
Brain Behavior and Immunity · Jan 16, 2025Peer-reviewedNeuroscience