Author

Paola Leone

Icahn School of Medicine at Mount SinaiORCID 0000-0002-1903-3596Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam C. MariD· 1 shared Asha Y. Caslin· 1 shared Cristina Gutiérrez‐VázqueziD· 1 shared Deepasri Ananth· 1 shared Diana M. Gilly Suarez· 1 shared Emma M. Smith· 1 shared Erli Wind-anderseniD· 1 shared Gerold BongersiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Adam C. MarORCID

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2 papers

Recent·Most cited

Oral vancomycin treatment alters levels of indole derivatives and secondary bile acids modulating the expression of mTOR pathway genes in astrocytes during EAE

Paola Bianchimano, Paola Leone, Emma M. Smith, Cristina Gutiérrez‐Vázquez, Erli Wind-andersen, Gerold Bongers, Sebastian Cristancho, Howard L. Weiner, José C. Clemente, Stephanie K. Tankou

This study shows vancomycin improves EAE recovery by altering gut microbiota, indole derivatives, and secondary bile acids, which modulate mTOR pathway gene expression in astrocytes.

Brain Behavior and Immunity · Jan 16, 2025Peer-reviewedNeuroscience

Mouse helpers ensure maternal-infant survival

Luisa Schuster, Violet J. Ivan, Diana M. Gilly Suarez, Renee Henderson, Asha Y. Caslin, Jessica L. Minder, Gurket Kaur, Shreya Sankar, Deepasri Ananth, Matilda Kirk, Sarah B. Winokur, Latika Khatri, Paola Leone, Karen E. Adolph, Robert C. Froemke, Adam C. Mar

The paper shows that experienced female mice can improve maternal-infant survival by assisting in caregiving and parturition, particularly for mice lacking the oxytocin receptor.

bioRxiv · Dec 26, 2022 · PreprintNeuroscience