Lactate receptor, HCAR1, in neonatal hypoxic-ischemic encephalopathy
Jennifer C. Burnsed, Angelina S. June, Maria Marlicz, Emmy Zucker, Ellie Kain-Kuzienski, Hannah Mulhern, Leanne Maharaj, Chengsan Sun, Suchitra Joshi, Huayu Sun, Jaideep Kapur
This study examines HCAR1 expression and function in neonatal brains, finding that HCAR1 modulates neuronal excitability and that its absence worsens hypoxic-ischemic seizures.
bioRxiv · Sep 16, 2025 · PreprintNeuroscience