Jaideep Kapur

This study examines changes in neuronal activation in the somatosensory and insular cortices during the transition from acute to chronic neuropathic pain.

The paper develops a 3D brain assembloid model to study Alzheimer's disease progression and identifies IGFBP pathways as therapeutic targets in APOE4 carriers.

This study investigates the mechanisms of reduced cortical cholinergic activity during focal seizures using an awake mouse model and electrophysiology, calcium imaging, and neurotransmitter sensing.

This study examines HCAR1 expression and function in neonatal brains, finding that HCAR1 modulates neuronal excitability and that its absence worsens hypoxic-ischemic seizures.

This study shows that progesterone receptor activation increases cold sensitivity and pain susceptibility in mice, suggesting a potential therapeutic target for chronic pain in women.

This study shows that progesterone receptors in the hippocampus and entorhinal cortex support spatial memory in male and female mice, which may aid in mate-finding and foraging.

This paper presents a deep learning-based closed-loop optogenetic system for seizure detection and neuromodulation, showing improved detection and reduced false positives in vivo.