Age-driven Dysregulation of murine Dendritic Cells is controlled by cell-intrinsic and extrinsic effects
Philipp Bloecher, Sunrito Mitra, Louise Guet, Emre Kilic, Zhilin Zou, Maximilian Sprang, Johannes U. Mayer
This study investigates age-related changes in dendritic cells across tissues, finding tissue-specific alterations in DC development and function, with preserved cell-intrinsic capabilities in aged bone marrow.
bioRxiv · May 26, 2026 · PreprintImmunology