Johannes U. Mayer

This study examines how tensile strain affects cancer-associated fibroblasts (CAFs) and normal fibroblasts (NFs) from oral squamous cell carcinoma (OSCC) in vitro, finding increased gap closure in CAFs under strain.

This study investigates age-related changes in dendritic cells across tissues, finding tissue-specific alterations in DC development and function, with preserved cell-intrinsic capabilities in aged bone marrow.

This study shows that CX3CR1+ macrophages are essential for maintaining immune balance and epithelial integrity in the epididymis and testis, with their depletion leading to immune dysfunction and fertility issues.

This paper shows that inhibiting KDM6B reduces monocyte activation and skin inflammation in a psoriasis model by restoring H3K27me3 and suppressing inflammatory gene expression.

The paper re-evaluates the identity of CD4+ CD56+ CD16+ cells in human PBMC, finding they resemble NKT cells rather than exTreg, and explores Treg stability and Tr17 induction for therapeutic applications.

The paper improves seqQscorer by integrating the ENCODE blocklist to enhance ChIP-seq quality assessment accuracy and efficiency.

This study shows that transformer models struggle to capture DNA's functional complexity, suggesting inherent limitations that scale cannot overcome.

This paper uses CRISPR/Cas9 to edit the acetylcholinesterase gene in Schistosoma mansoni eggs, resulting in reduced AChE activity and decreased granuloma size in mice.