Integrated spatial and single-cell transcriptomic analysis of aggressive glioblastoma growth dynamics.
Clara Alves-Pereira, Gyeong Dae Kim, Ngima D. Sherpa, Kayla Colvin, Saad M. Khan, Khanh P. Phan, Anthony Z. Wang, Ian F. Dunn, Tanner Michael Johanns, Erdyni Tsitsykov, Rupen Desai, Gavin P. Dunn, Allegra A. Petti
This study compares two murine glioblastoma models using single-cell and spatial transcriptomics to reveal distinct tumor-immune dynamics and their correlation with human GBM survival.
bioRxiv · May 14, 2026 · PreprintCancer Biology