Author

Eric Fogarty

University of South Dakota

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Developmental Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

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Jennifer deRiso· 1 shared Kameswaran SurendraniD· 1 shared Madhusudhana R. JangaiD· 1 shared Malini Mukherjee· 1 shared

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2020-2020 · peak 1/yr

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Jennifer deRiso

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Foxi1 inactivation rescues loss of principal cell fate selection in Hes1-deficient kidneys but does not ensure maintenance of principal cell gene expression.

Malini Mukherjee, Jennifer deRiso, Madhusudhana R. Janga, Eric Fogarty, Kameswaran Surendran

This study shows that Hes1 represses Foxi1 to ensure principal cell fate selection in kidney collecting ducts, but Foxi1 inactivation does not fully restore principal cell gene expression.

Developmental Biology · Aug 13, 2020Peer-reviewedDevelopmental Biology