Kidney collecting duct cell type composition is regulated by Notch signaling via modulation of mTORC1
Jennifer deRiso, Malini Mukherjee, Madhusudhana R. Janga, Alicia Simmons, Michael S. Kareta, Jianning Tao, Indra Chandrasekar, Kameswaran Surendran
This study identifies Hes1 as a Notch signaling target that regulates mTORC1 activity to maintain distinct epithelial cell types in kidney collecting ducts.
bioRxiv · Apr 9, 2024 · PreprintDevelopmental Biology