Phosphosite T674A mutation in kinesin family member 3A fails to reproduce tissue and ciliary defects characteristic of CILK1 loss of function
Casey D. Gailey, Eric J. Wang, Li Jin, Sean Ahmadi, David L. Brautigan, Xudong Joshua Li, Wenhao Xu, Michael M. Scott, Zheng Fu
The paper shows that mutating KIF3A's phosphorylation site T674 to Ala in mice does not reproduce the severe ciliopathy defects seen with CILK1 loss of function.
Developmental Dynamics · Sep 16, 2020Peer-reviewedDevelopmental Biology