Hippocampal Neuroinflammation and Altered Peripheral Neurobiological Protein Profile in Experimental Arthritis and Systemic Juvenile Idiopathic Arthritis
Xingzhao Wen, Heshuang Qu, Małgorzata Benedyk‐Machaczka, Daphne Chen, Erik Sundberg, Erik Melén, Maria Altman, Cecilia Aulin, Helena Erlandsson Harris
This study identifies altered neurobiological protein profiles and hippocampal neuroinflammation in systemic juvenile idiopathic arthritis, with HMOX2 as a biomarker and IL-6/IL-18 as key drivers.
EBioMedicine · Jun 16, 2026Peer-reviewedImmunology