Author

Erik Melén

Karolinska InstitutetORCID 0000-0002-8248-0663Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:eQTL / molecular QTL mapping· 1 Approach:experimental assay· 1

Frequent Co-Authors

Cecilia AuliniD· 2 shared Cheng‐Jian XuiD· 2 shared Dan MasoniD· 2 shared Darina CzamaraiD· 2 shared Erik Sundberg· 2 shared Helena Erlandsson HarrisiD· 2 shared Henning W. TiemeieriD· 2 shared Heshuang QuiD· 2 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersImmunology

Cecilia AulinORCID

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4 papers

Recent·Most cited

ImmunologyEBioMedicinePeer-reviewedJun 16, 2026

Hippocampal Neuroinflammation and Altered Peripheral Neurobiological Protein Profile in Experimental Arthritis and Systemic Juvenile Idiopathic Arthritis

Xingzhao Wen, Heshuang Qu, Małgorzata Benedyk‐Machaczka…·Helena Erlandsson Harris

This study identifies altered neurobiological protein profiles and hippocampal neuroinflammation in systemic juvenile idiopathic arthritis, with HMOX2 as a biomarker and IL-6/IL-18 as key drivers.

DOI 10.1016/j.ebiom.2026.106330

humanproteomics

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ImmunologyFrontiers in ImmunologyPeer-reviewedAug 7, 2025

Inflammation-profiling reveals activated pathways and biomarkers with predictive potential in oligoarticular JIA

Xingzhao Wen, Cecilia Aulin, Erik Sundberg…·Helena Erlandsson Harris

This study profiles inflammation in oligoarticular JIA using proteomics, identifying biomarkers correlated with disease activity and progression.

2 citations

humanproteomics

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Genetic & Genomic MedicinemedRxivPreprintFeb 29, 2024

Epigenetic timing effects on child developmental outcomes: A longitudinal meta-regression of findings from the Pregnancy And Childhood Epigenetics Consortium

Alexander Neumann, Sara Sammallahti, Marta Cosín‐Tomás…·Charlotte A. M. Cecil

This study uses longitudinal meta-regression to examine how DNA methylation effects on child health outcomes vary by timing, finding larger effects in childhood but noisier associations and time-specific signals.

2 citations

humanDNA methylation

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Genetic & Genomic MedicineNature GeneticsPeer-reviewedSep 1, 2021

Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

Josine L. Min, Gibran Hemani, Eilis J. Hannon…·Marinus H. van IJzendoorn

The paper identifies genetic variants influencing DNA methylation in blood and shows their associations with complex traits and diseases, but finds limited direct causality.

508 citationstop 1%

humanDNA methylation

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