The combination of elevated neuronal activity and mitochondrial damage induces Pink1-dependent mitophagy in axons
Serena R. Wisner, Chris Stein, Erin E Smith, Mrinalini Hoon, Catherine M. Drerup
The paper shows that combining elevated neuronal activity with mitochondrial damage increases mitophagy in axons, requiring Pink1.
bioRxiv · Dec 26, 2025 · PreprintNeuroscience