Mrinalini Hoon

The combination of elevated neuronal activity and mitochondrial damage induces Pink1-dependent mitophagy in axons

The paper shows that combining elevated neuronal activity with mitochondrial damage increases mitophagy in axons, requiring Pink1.

Nanophysiology Approach Reveals Diversity in Calcium Microdomains across Zebrafish Retinal Bipolar Ribbon Synapses

The paper uses imaging to study calcium signals in zebrafish retinal bipolar cells, finding variations in local calcium levels related to ribbon size and active zone extent.

Ankyrins are essential at the photoreceptor synapse in the mouse outer retina

The paper identifies Ankyrins as critical for synaptic connectivity between horizontal cells and photoreceptors in the mouse retina through single-cell RNA sequencing and functional analysis.

A non-conducting role of the Cav1.4 Ca2+ channel drives homeostatic plasticity at the cone photoreceptor synapse

The paper shows that a non-conducting Cav1.4 Ca2+ channel is essential for cone synaptogenesis, and its absence is compensated by Cav3 channels, leading to normal cone-mediated vision in knock-in mice.

The retina's neurovascular unit: Mueller glial sheaths and neuronal contacts

This study investigates the structure and function of Muller glial sheaths in the retina's vascular layers, revealing compartmentalized interactions between glia and vessels.

Dendro-somatic synaptic inputs to ganglion cells violate receptive field and connectivity rules in the mammalian retina

The paper identifies a retinal circuit where A2 amacrine cells inhibit OFF ganglion cells in the ON layer, contradicting established connectivity and receptive field rules.

A high-density narrow-field inhibitory retinal interneuron with direct coupling to Müller glia

The paper identifies a new inhibitory retinal amacrine cell type, MAC, that forms direct electrical and chemical synapses with Müller glia, revealing neuron-glia coupling in the mammalian retina.