Neonatal hyperoxia inhibits proliferation of atrial cardiomyocytes by suppressing fatty acid synthesis
Ethan David Cohen, Min Yee, George Arthur Porter Jr., Erin Ritzer, Andrew McDavid, Paul S. Brookes, Gloria Pryhuber, Michael A. O’Reilly
This study shows that neonatal hyperoxia inhibits atrial cardiomyocyte proliferation by suppressing fatty acid synthesis genes, leading to diastolic heart failure.
JCI Insight · Jan 28, 2021Peer-reviewedDevelopmental Biology