Systems BiologyGenome ResearchPeer-reviewed
Binding specificities of human RNA binding proteins towards structured and linear RNA sequences
Arttu Jolma, Jilin Zhang, Estefanía Mondragón…·Jussi Taipale
The paper identifies binding specificities of human RNA-binding proteins using HTR-SELEX, revealing that 70% bind linear sequences and 30% bind structured motifs, with novel roles for ZC3H12A/B/C in viral transcript degradation.
5 citations