Leveraging current steering and the biophysics of spike generation for cellular-resolution electrical stimulation of neurons
Praful Krishna Vasireddy, Ramandeep S. Vilkhu, Amrith Lotlikar, Jeff B. Brown, AJ Phillips, Alex R. Gogliettino, Madeline Rose Hays, Claire Baum, Ethan J. Kato, Aviv Sharon, Paweł Hottowy, Alexander Sher, Alan M Litke, Subhasish Mitra, Nishal P. Shah, E. J. Chichilnisky
This study develops a framework for cellular-resolution electrical stimulation of neurons using current steering and biophysical models, demonstrating its effectiveness in targeting retinal ganglion cells.
Cell Reports · Jan 29, 2026Peer-reviewedBioengineering