Paweł Hottowy

Electrical stimulation precisely reproduces naturalistic spiking activity in complete and intermixed neural populations in the primate retina

This study uses electrical stimulation to replicate natural spiking activity in primate retinal neurons, achieving lower variability than visual stimuli.

Leveraging current steering and the biophysics of spike generation for cellular-resolution electrical stimulation of neurons

This study develops a framework for cellular-resolution electrical stimulation of neurons using current steering and biophysical models, demonstrating its effectiveness in targeting retinal ganglion cells.

Understanding responses to multi-electrode epiretinal stimulation using a biophysical model

The paper develops a biophysical model to study retinal ganglion cell responses to multi-electrode stimulation and validates it with experimental data from macaque retinas.

Precise control of neural activity using dynamically optimized electrical stimulation

This paper introduces a dynamically optimized electrical stimulation method to enhance neural activity control in retinal implants, showing improved visual stimulus reconstruction compared to static methods.

Local contribution to the somatosensory evoked potentials in rat's thalamus

The paper shows that local thalamic LFP can be reliably recovered using kCSD, even without concurrent cortical recordings, by removing a negative component from cortex.

Inference of Electrical Stimulation Sensitivity from Recorded Activity of Primate Retinal Ganglion Cells

The paper infers electrical stimulation sensitivity of primate retinal ganglion cells from their recorded activity, showing that electrode features and cell compartmental differences affect stimulation thresholds.

High-fidelity reproduction of visual signals by electrical stimulation in the central primate retina

This study evaluates the effectiveness of focal electrical stimulation in the central macaque retina to reproduce visual signals, finding higher expected image quality compared to the peripheral retina.

Focal Electrical Stimulation of Human Retinal Ganglion Cells for Vision Restoration

This study demonstrates that high-fidelity electrical stimulation of human retinal ganglion cells is achievable with extracellular stimulation, validated through ex vivo experiments and comparison to macaque retina results.

Epiretinal stimulation with local returns enhances selectivity at cellular resolution

The paper evaluates local return stimulation to improve selective activation of retinal ganglion cells at cellular resolution in isolated primate retina.

Electrical Stimulus Artifact Cancellation and Neural Spike Detection on Large Multi-Electrode Arrays

The paper develops a Gaussian Process model to cancel electrical stimulation artifacts and detect neural spikes in multi-electrode recordings, achieving low error rates and real-time compatibility.