Alex R. Gogliettino

This study develops a framework for cellular-resolution electrical stimulation of neurons using current steering and biophysical models, demonstrating its effectiveness in targeting retinal ganglion cells.

The paper examines how different primate retinal ganglion cell types respond to natural scenes, finding stereotyped response kinetics and distinct firing pattern repertoires across cell types.

The paper decomposes retinal ganglion cell electrical images to infer cell types and functional properties using a novel optimization-based algorithm.

The paper develops a biophysical model to study retinal ganglion cell responses to multi-electrode stimulation and validates it with experimental data from macaque retinas.

This study shows fixational eye movements improve retinal signal precision by enhancing spike timing and cell interactions in macaque retinas.

This paper introduces a dynamically optimized electrical stimulation method to enhance neural activity control in retinal implants, showing improved visual stimulus reconstruction compared to static methods.

The paper trains a convolutional neural network to predict retinal ganglion cell responses to natural images in macaques and humans, finding it more accurate than a linear-nonlinear model.

The paper infers light responses of primate retinal ganglion cells using electrical features, achieving moderate correlation with measured firing rates.

The paper infers electrical stimulation sensitivity of primate retinal ganglion cells from their recorded activity, showing that electrode features and cell compartmental differences affect stimulation thresholds.

This study evaluates the effectiveness of focal electrical stimulation in the central macaque retina to reproduce visual signals, finding higher expected image quality compared to the peripheral retina.

This study demonstrates that high-fidelity electrical stimulation of human retinal ganglion cells is achievable with extracellular stimulation, validated through ex vivo experiments and comparison to macaque retina results.

The paper compares functional properties of major retinal ganglion cell types between humans and macaques using similar experimental methods, finding close parallels in their responses and organization.

This study shows that Tet2 negatively regulates long-term memory fidelity by modulating DNA methylation in hippocampal neurons.