Author

Eugene Urrutia

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 4

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Organism:human· 2 Organism:mouse· 2 Research Focus:variant calling· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:deconvolution· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Yuchao JiangiD· 4 shared Nancy Ruonan ZhangiD· 2 shared Aatish ThennavaniD· 1 shared Charles M. PerouiD· 1 shared Fei ZouiD· 1 shared Haibo ZhouiD· 1 shared Hao CheniD· 1 shared Ioannis N. AnastopoulosiD· 1 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersBioinformatics

Yuchao JiangORCID

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4 papers

Recent·Most cited

SCDC: Bulk Gene Expression Deconvolution by Multiple Single-Cell RNA Sequencing References

Meichen Dong, Aatish Thennavan, Eugene Urrutia, Yun Li, Charles M. Perou, Fei Zou, Yuchao Jiang

SCDC improves bulk RNA-seq deconvolution by integrating multiple scRNA-seq reference datasets, achieving better accuracy in cell-type decomposition.

Briefings in Bioinformatics · Dec 3, 2019Peer-reviewedBioinformatics

Destin: toolkit for single-cell analysis of chromatin accessibility

Eugene Urrutia, Li Chen, Haibo Zhou, Yuchao Jiang

Destin is a framework for analyzing scATAC-seq data, outperforming existing methods in clustering and identifying cell type-specific associations with schizophrenia GWAS loci.

Bioinformatics · Feb 25, 2019Peer-reviewedBioinformatics

CODEX2: full-spectrum copy number variation detection by high-throughput DNA sequencing

Yuchao Jiang, Rujin Wang, Eugene Urrutia, Ioannis N. Anastopoulos, Katherine L. Nathanson, Nancy Ruonan Zhang

CODEX2 improves CNV detection sensitivity and reduces false discoveries in whole-exome and targeted sequencing data.

Genome biology · Nov 26, 2018Peer-reviewedBioinformatics

Integrative pipeline for profiling DNA copy number and inferring tumor phylogeny

Eugene Urrutia, Hao Chen, Zilu Zhou, Nancy Ruonan Zhang, Yuchao Jiang

The paper introduces a computational pipeline called MARATHON for copy number profiling and tumor phylogeny inference, addressing challenges in cancer genomics.

Bioinformatics · Feb 2, 2018Peer-reviewedBioinformatics