Epigenetic histone modifications H3K36me3 and H4K5/8/12/16ac induce open polynucleosome conformations via different mechanisms
Yi-Yun Lin, Peter K Müller, Evdoxia Karagianni, Nicola Hepp, Felix Mueller‐Planitz, Willem Vanderlinden, Jan Lipfert
This study examines how H3K36me3 and H4K5/8/12/16ac histone modifications affect nucleosome structure and interactions in tri-nucleosome arrays, revealing distinct mechanisms for inducing open conformations.
Journal of Molecular Biology · Jun 20, 2024Peer-reviewedBiophysics