Epac1 regulates cellular SUMOylation by promoting the formation of SUMO-activating nuclear condensates
W. Yang, W. G. Robichaux, F. C. Mei, W. Lin, L. Li, S. Pan, M. A. White, Y. Chen, X. Cheng
This study shows Epac1 regulates SUMOylation by forming nuclear condensates in response to cAMP, linking stress responses to SUMOylation dynamics.
bioRxiv · Jan 12, 2022 · PreprintCell Biology