Closure of the gamma-tubulin ring complex by CDK5RAP2 activates microtubule nucleation
Y. Xu, H. Munoz-Hernandez, R. Krutyholowa, F. Marxer, F. Cetin, M. Wieczorek
This study determines the structure of the gamma-tubulin ring complex (gamma-TuRC) activated by CDK5RAP2 and shows how it promotes microtubule nucleation by closing the gamma-tubulin ring.
bioRxiv · Dec 14, 2023Biochemistry