Unexpected Loss of Sensitivity to the nAChR Antagonist Activity of Mecamylamine and DHβEin Nicotine-Tolerant C57BL/6J Mice
The paper examines how chronic nicotine exposure affects the ability of nAChR antagonists to counteract nicotine's effects in mice, finding reduced antagonism during treatment.
bioRxiv · Nov 28, 2018 · PreprintPharmacology & Toxicology