Ancestral versus Modern Substrate Scope in Family-1 Glycosidases
L. I. Gutierrez-Rus, D. Petrovic, P. Schneider, K. Zorn, G. Gamiz-Arco, R. Romero-Zaliz, I. Suarez-Martin, L. De Maria, F. Falcioni, V. A. Risso, M. A. Hayes, J. M. Sanchez-Ruiz
This study compares the substrate scope of a modern and ancestral family-1 glycosidase, finding the ancestral enzyme more efficient with large aglycon-containing flavonoid glycosides.
bioRxiv · Apr 11, 2024Biochemistry